Product Name :
25-Hydroxyvitamin D2 (CAS 21343-40-8)

Synonym :
25-Hydroxyergocalciferol; 25-Hydroxycalciferol

Application :
25-Hydroxyvitamin D2 is biologically active vitamin D2 metabolite

CAS:
21343-40-8

Purity:
≥98%

Molecular Weight:
412.65

Formula :
C28H44O2

Physical state:
Solid

solubility :

Shipping Condition :
Store at -20° C

Melting point:
88.0-95.0° C

SMILES:
C[C@H](/C=C/[C@H](C)C(C)(C)O)[C@H]1CC[C@@H]\\2[C@@]1(CCC/C2=C\\C=C/3\\C[C@H](CCC3=C)O)C

References:
:Rapid and sensitive high-performance liquid chromatographic method for simultaneous determination of retinol, alpha-tocopherol, 25-hydroxyvitamin D3 and 25-hydroxyvitamin D2 in human plasma with photodiode-array ultraviolet detection. | Alvarez, JC. and De Mazancourt, P. 2001. J Chromatogr B Biomed Sci Appl. 755: 129-35. PMID: 11393696Associations of 25-hydroxyvitamin D2 and D3 with cardiovascular risk factors in childhood: cross-sectional findings from the Avon Longitudinal Study of Parents and Children. | Williams, DM., et al. 2012. J Clin Endocrinol Metab. 97: 1563-71. PMID: 22344194Standardization of measurements of 25-hydroxyvitamin D3 and D2. | Thienpont, LM., et al. 2012. Scand J Clin Lab Invest Suppl. 243: 41-9. PMID: 22536761UV-dependent production of 25-hydroxyvitamin D2 in the recombinant yeast cells expressing human CYP2R1. | Yasuda, K., et al. 2013. Biochem Biophys Res Commun. 434: 311-5. PMID: 23548573Higher 25(OH)D2 is associated with lower 25(OH)D3 and 1,25(OH)2D3. | Swanson, CM., et al. 2014. J Clin Endocrinol Metab. 99: 2736-44. PMID: 2482848825-Hydroxyvitamin D2 /D3 levels and factors associated with systemic inflammation and melanoma survival in the Leeds Melanoma Cohort. | Newton-Bishop, JA., et al. 2015. Int J Cancer. 136: 2890-9. PMID: 25403087Quantitation of 25-hydroxyvitamin D2 and D3 in serum and plasma by LCMS/MS. | Lee, D., et al. 2015. Bioanalysis. 7: 167-78. PMID: 25587834A candidate reference measurement procedure for quantifying serum concentrations of 25-hydroxyvitamin D3 and 25-hydroxyvitamin D2 using isotope-dilution liquid chromatography-tandem mass spectrometry. | Mineva, EM., et al. 2015. Anal Bioanal Chem. 407: 5615-24. PMID: 2596714925-Hydroxyvitamin D isomerizes to pre-25-hydroxyvitamin D in solution: considerations for calibration in clinical measurements. | Bedner, M. and Lippa, KA. 2015. Anal Bioanal Chem. 407: 8079-86. PMID: 26359234Magnesium status and supplementation influence vitamin D status and metabolism: results from a randomized trial. | Dai, Q., et al. 2018. Am J Clin Nutr. 108: 1249-1258. PMID: 30541089Variation in plasma 25-hydroxyvitamin D2 and D3 in normal pregnancy with gestational age, sampling season, and complications: A longitudinal cohort study.Buy6-(tert-Butoxy)-6-oxohexanoic acid | Orvik, AB.4,6-Dimethyl-1H-indole Chemical name , et al.PMID:33449395 2020. PLoS One. 15: e0231657. PMID: 32302333Improved Recognition of 25-Hydroxyvitamin D2 by 2 Automated Immunoassays. | Geno, KA., et al. 2020. J Appl Lab Med. 5: 1287-1295. PMID: 32529210Measurement of plasma 25-hydroxyvitamin D2, 25-hydroxyvitamin D3 and 3-epi-25-hydroxyvitamin D3 in population of patients with cardiovascular disease by UPLC-MS/MS method. | Abouzid, M., et al. 2020. J Chromatogr B Analyt Technol Biomed Life Sci. 1159: 122350. PMID: 3289076925-hydroxyvitamin D is a predictor of COVID-19 severity of hospitalized patients. | Nguyen, NN., et al. 2022. PLoS One. 17: e0268038. PMID: 35503795Quantification of 25-Hydroxyvitamin D2 and D3 Using Liquid Chromatography-Tandem Mass Spectrometry. | Munar, A., et al. 2022. Methods Mol Biol. 2546: 539-544. PMID: 36127620