Product Name :
UBE3C Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
HectH2 antibody KIAA0010 antibody KIAA10 antibody Ube3c antibody UBE3C_HUMAN antibody Ubiquitin protein isopeptide ligase (E3) antibody Ubiquitin protein ligase E3C antibody Ubiquitin-protein ligase E3C antibody
Function :
E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.1206981-68-1 custom synthesis miscellaneous:A cysteine residue is required for ubiquitin-thioester formation. pathway:Protein modification; protein ubiquitination. Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain. Contains 1 IQ domain. subunit:Interacts with 26S proteasomes. Binds CAND2. tissue specificity:Highly expressed in skeletal muscle. Detected at much lower levels in kidney and pancreas.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthesized peptide derived from the Internal region of human UBE3C.
Species reactivity:
Human
Verify application:
WB
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.Formula of 852913-25-8
Storage buffer solution:
Liquid in PBS containing 50% glycerol, 0.PMID:33687943 5% BSA and 0.02% sodium azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
125 kDa
Positive control :
Bone marrow,Lung,Placenta,