Product Name :
PPP1R1A Recombinant Rabbit Monoclonal Antibody [SN0756]
Predicted band size :
19 kDa
Observed band size :
27 kDa
Synonyms:
I 1 antibody I-1 antibody I1 antibody Inhibitor 1 antibody IPP 1 antibody IPP-1 antibody IPP1 antibody Ppp1r1a antibody PPR1A_HUMAN antibody Protein phosphatase 1 regulatory (inhibitor) subunit 1A antibody 展开
Function :
The inhibitor of protein phosphatase 1 (IPP-1, I-1) plays a role in regulating the phosphorylation of other proteins, and is itself phosphorylated by a cyclic AMP-dependent protein kinase. IPP-1 is present in skeletal muscles and in distinct neuronal systems of the brain. The localization and expression of IPP-1 suggests that it may play discrete roles in certain regions and developing stages of the brain, independent of the regulation of protein phosphatase type 1 (PP-1). PP-1 binds to both phosphorylated and dephosphorylated IPP-1. Conversion of PP-1 to an Mn2+-dependent state appears to play a role in its regulation by IPP-1. IPP-1 attenuates the activity of glycogen phosphorylase and is thought to play an important role in the hormonal control of glycogen metabolism.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human PPP1R1A aa 1-50 / 171.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IF-Cell, IF-Tissue, IHC-P, FC, IP
Coupling :
unconjugated
Clone number:
SN0756
RRID:
AB_3073460
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.8-Bromo-3-chloroisoquinoline manufacturer Aliquot store at -20℃ or -80℃.Price of 2422999-74-2 Avoid repeated freeze / thaw cycles.PMID:33557960
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 19 kDa
Positive control :
Mouse brain tissue lysate, rat brain tissue lysate, N2A, SH-SY5Y, SHG-44, human kidney tissue, human pancreas tissue, mouse kidney tissue, mouse pancreas tissue, rat kidney tissue, rat pancreas tissue.