Product Name :
2-Amino-6,8-dihydroxypurine Hydrochloride (CAS 1246818-54-1)
Synonym :
8-Hydroxyguanine Hydrochloride
Application :
2-Amino-6,8-dihydroxypurine Hydrochloride is a diagnostic product of nucleic acid oxidative damage
CAS:
1246818-54-1
Purity:
≥90%
Molecular Weight:
203.59
Formula :
C5H5N5O2•HCl
Physical state:
Solid
solubility :
Soluble in water (<1 mg/ml at 25° C), ethanol (sparingly), DMSO (sparingly), DMF (sparingly), and 2 M NaOH (1 mg/ml).6-Bromo-[1,2,4]triazolo[4,3-b]pyridazine supplier
Shipping Condition :
Store at room temperature
Melting point:
SMILES:
C12=C(NC(=NC1=O)N)NC(=O)N2.Cl
References:
:Assay of excised oxidative DNA lesions: isolation of 8-oxoguanine and its nucleoside derivatives from biological fluids with a monoclonal antibody column. | Park, EM., et al. 1992. Proc Natl Acad Sci U S A. 89: 3375-9. PMID: 1565629DNA strand breakage and base modification induced by hydrogen peroxide treatment of human respiratory tract epithelial cells. | Spencer, JP., et al.Buy3-Isopropylpyridin-2(1H)-one 1995.PMID:33432591 FEBS Lett. 374: 233-6. PMID: 7589542Oxidative DNA base damage and antioxidant enzyme activities in human lung cancer. | Jaruga, P., et al. 1994. FEBS Lett. 341: 59-64. PMID: 8137923DNA damage by peroxynitrite characterized with DNA repair enzymes. | Epe, B., et al. 1996. Nucleic Acids Res. 24: 4105-10. PMID: 8932358Oxidative decay of DNA. | Beckman, KB. and Ames, BN. 1997. J Biol Chem. 272: 19633-6. PMID: 9289489